SCIENCE AND MARRIAGE

Marriage has gone beyond what it use to be, it now involves all facet of marriage.
During the days of the old, our parents, before they give their children out for marriage they go on an underground investigation to know more about the other family, Like if they have any trace of madness or any sort of sickness or disease, if they have an ongoing family curse, and sort of. But they had no capability to find out one thing which science has proven today to be the an issue that propounds most marriage calamities - GENOTYPE!
Genotype is the genetic makeup of an individual with reference to a trait or multiple traits. They are the collection of genes passed from parents to the children. Alleles or Allelomorphs are also referred to as the genes. Children born of a parent will have different genotype. Exceptions are seen in cases of twins or multiple births that are fertilized from the same egg. Human beings have two alleles with each pair inherited from each parent. An allele represents a gene.
Before the advent of modern medicine. There was high mortality and infant death rates. All these children lost to the cold hands of death were referred to as "abikus". All these happened because there was no knowledge on blood group or genotype. People that get married irrespective of their genetic makeup should not be blamed for their ignorance. But with the advent of modern medicine, biological explanations are now being made on the causes of infant death rate, this led to the discovery of sickle cells in Africa, especially in Nigeria. Before marriage, partners should be aware of their genotypes and blood group as the society no long provides excuse for this ignorance. Parents should check the genotype of their children during pregnancy or immediately after birth. This will help to know the health status of the child and what they have to do to sustain and maintain the child's health.
There are four genotypes in humans - AA, AS, SS and AC. AC genotype is not so common and popular unlike the other three. SS and AC are the abnormal genotypes or the sickle cells.
But the common ones are AA AS and SS.
Marriage has involved scientific and mathematics theories.
Now let's look at this mathematically:
AS + AS = AA, AS, AS, SS... well this is not really advisable enough.
AS + AA = AA, AA, AS, AS... This compatibility is advisable at least to an extent.
AS + SS = AS, AS, SS, SS. This is not to be encouraged at all.
AA + SS = AS, AS, AS, AS... Well, this is still okay.
AA + AA = AA, AA, AA, AA....what more can you ask for but to start thinking of how to raise those lovely kids! Simply the best!
SS + SS = SS, SS, SS, SS! NO COMMENT! You know what I mean! Well miracle still happens isn't it?
But remember the Bible said "thou shall not tempt the Lord thy God".
You need not put God into test when you know the right. Even God said it that you servant, use thy wisdom!
I'm not saying SS shouldn't marry, but if ever they would, they should try to marry AA genotype.

The knowledge of genotype is important when choosing life partners. Intending couples should know both their own genotype as well as their partner's genotype at the early stage of their relationship before they are well rooted in love and emotions. Emotions and time spent in the relationship can cloud people’s judgment or decision to break up if they are not compatible, thus, giving birth to sickle cell children and subjecting themselves and their children to pain, torture and agony. Even if you wouldn't consider yourself, consider the future of the innocent kids, don't bring them to the world to suffer!

People with the genotype AA are prone to malaria sickness at their early ages. Sickle cell arises when there is any blockage in the blood vessels which inhibits the flow of oxygen. When the red blood cell do not have the required oxygen, there will be changes in its original shape (disc shape) to a "Sickle-like" or "crescent-like shape", Thus, the name "sickle cell". Sickle cell patients experience severe pains in body parts that lack oxygen flow. Their bone marrows will fail to produce red blood cells and this result to anemia. To save this crisis, blood is usually transfused to them.

In terms of compatibility, someone with AA genotype can marry anybody. It is safe for someone with AS to marry someone with AA genotype. The combinations of AS and AS, and AS should not be risked. There is probability of having a SS. Although. Two sickle cells should not even have a relationship or get married. Individuals with the AA genotype should help you prevent genetic abnormalities by marrying the AS and SS.  By this, we are hopeful to eradicate sickle cells in the world.
Don't be ignorant anymore, try as much as possible to know your genotype compatibility before marriage.
Many people has lost out on good and solid relationships not because one party was defaulting but because they were not egocentric, because they considered the future of some great unborn kids.
Don't let love cover your eyes nor blindfold you from seeing the reality.
Let's make the world a better place!